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However, antigen sampling of luminal microbes is necessary for immunological development, bacterial clearance and the production of IgA, the latter of which is important in restricting microbial adhesion to the mucosal layer and coating commensal species to limit their interaction with immune system (Johansen et al

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Therapies such as ambroxol, a small molecule with lysosomal-enhancing properties, and buntanetap tartrate, a compound that can reduce neurotoxic protein levels, are some of the novel therapies currently under investigation for their potential to restore cellular balance and slow the progression of PD