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Given the FDAs April 2025 alert, informed consent for compounded topical finasteride should cover systemic absorption risk, known side effects (sexual, neuropsychiatric), transfer risk to household members (especially women of childbearing age), and the non-FDA-approved status of the formulation

The peptide upregulates MMP-2 expression in dermal fibroblasts by 85%, facilitating breakdown of damaged collagen and enabling cellular migration through dense matrix environments, while simultaneously enhancing production of tissue inhibitors of metalloproteinases (TIMPs) to prevent excessive degradation

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