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Description

One mechanism that contributes to cytochrome c detachment from IMM involves cardiolipin oxidation because oxidized cardiolipin has a much lower affinity for cytochrome c than the reduced form

& Swartz, M

Although approved multi-agent chemotherapy regimens offer an incremental advance over single-agent treatments, the best available treatment cocktails are only marginally effective, and virtually all PDAC eventually becomes resistant to these treatments ( 1, 2 )