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Nanoparticles responsive to GSH are capable of delivering both chemotherapeutic drugs and inhibitors, such as an oxaliplatin-based prodrug combined with an IDO-1 inhibitor (indoleamine 2,3-dioxygenase 1)

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Bioinformatic approaches for the analysis of DNA methylation Although the methodologies described in the previous section enable the detection of differential methylation at single cytosines (DMCs), DNA methylation alterations may also occur across multiple intragenic and intergenic loci, resulting in differentially methylated regions (DMRs)

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