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Their study in male mice and macaques demonstrated that IMA-1 disrupts the arachidonate 12-lipoxygenaseacetyl-CoA carboxylase 1 interaction, thereby treating NAFLD without inducing hyperlipidemia [74]

To learn more on the consequences of Stard7 deficiency in Wnt-driven tumor initiation on transcriptional reprogramming, we conducted RNA Sequencing experiments combined with GSEA with intestinal tumors from both Apc +/Min /Stard7 IEC and Apc +/Min /Stard7 Lox/lox mice