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Xiaogang Qin, [email protected] These authors have contributed equally to this work This article was submitted to Cancer Immunity and Immunotherapy, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

4.4.3 Anti-inflammatory effects in acute central nervous system injury After acute injuries such as stroke and trauma, the activation of microglia and the infiltration of peripheral immune cells into ischemic tissues may trigger a robust and deleterious neuroinflammatory response (261)

Variable TQ content in commercially available NS products is another confusing issue in their varied efficacy, with requests for regulating them for TQ content (313, 314)

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