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Excess copper accumulates in the liver, brain, kidney, muscles, and other tissues, which can cause common liver diseases, cirrhosis, neuropsychiatric disorders, and, rarely, muscle lesions ( Duchenne muscular dystrophy (DMD) is a rare X-linked recessive muscular disease occurring in 4.6/100,000 male newborns ( DMD gene, is the main pathogenesis of DMD, resulting in progressively aggravated skeletal muscle weakness and atrophy, intellectual development disorders, and cardiomyopathy ( WD and DMD are rare diseases involving multiple systems

While this provides short-term symptomatic relief, the remaining cartilage is more susceptible to wear and accelerated degeneration

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