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The isolated proteins were separated by sodium dodecyl sulfatepolyacrylamide gel electrophoresis (SDSPAGE) (Millipore, USA)

Additionally, the reduced plasma levels of brain-derived neurotrophic factor (BDNF) observed in BIPN patients may be associated with BTZ-mediated inhibition of platelet aggregation and activation, which in turn leads to decreased BDNF release and consequently impairs its neuroregenerative effects on peripheral nerves (Nishiwaki et al., 2020)

It has a role in maintaining the integrity of skin and mucous membranes

Injections can be crucial for restoring adequate levels, promoting better health, and preventing the long-term consequences of deficiency