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Nat Cell Biol 2014, 16 : 992-1003, 1001-15

Trastuzumab: more than a guide in HER2-Positive cancer nanomedicine

Growing evidence indicates that targeting these metabolic dependencies may offer therapeutic benefit, whether through dietary approaches like the ketogenic diet, pharmacologic inhibition of glycolysis and glutaminolysis, or disruption of mitochondrial activity and hypoxia/angiogenesis pathways