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Lima et al., 2017

The glutathione peptide of one inhibitor, termed productive binding, occupies the G-subsite with multiple interactions similar to those observed for other glutathione S-transferases, while the glutathione backbone of the second inhibitor, termed unproductive binding, exhibits only weak interactions mediated by two polar contacts

However, with the growing interest in NAD+ therapy , understanding the ideal NAD dosage per day and frequency is crucial to achieving optimal results while minimizing potential side effects