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Together, our data suggest that sustained systemic inflammation and persistent localized BBB dysfunction is a key feature of long COVID-associated brain fog

PKU is the most common metabolic defect of an amino acid in humans, with an average prevalence worldwide of 1:10,000 live births [182]

Cigarette smoking is associated with decreased semen volume, sperm count, and sperm motility, as well as worse infertility treatment outcomes

Activation of TMEM19 on microglial cells stimulates the secretion of cytokines and growth factors (including VEGF, PDGF, FGF-2, IGF-1 and BDNF) that support photoreceptor integrity and maintain vascular networks