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Elevation of intracellular Ca 2+ activates scramblase to ensure PS externalization, opens the Gardos channels, resulting in K + efflux and subsequent cell shrinkage, and mobilizes calpain, leading to cytoskeleton degradation and membrane microvesiculation [78]

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Recently, a series of qualitative, or quantitative methods have been developed to measure -PL concentration, including: (1) colorimetric methods with the acidic dye [26], e.g., molybdosilicate anion [27], poly R-478.24, or dipicrylamine [28]

10.2164/jandrol.110.012823