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These technologies enable identification of de novo target interactions, optimization of drug combinations, and prediction of drug efficacy along with toxicity, which may eventually translate into more effective and safer therapies for AD and other complex diseases (Vrahatis et al., 2023)

In addition, the widely practiced applications of semen cryopreservation significantly enhance the reproductive efficiency and commercial value of livestock breeding (3, 4)

suggested that an organized process of senescence in, and ultimately removal of, a subgroup of endometrial stromal cells contributes to the overall remodeling and regrowth of the endometrium during the proliferative phase ( Cellular senescence is a phenomenon described in proliferative tissue including the endometrium and can occur under physiologic conditions when a cell reaches its final telomere length or under the influence of oxidative stress and other stressors such as DNA damage, inflammation, and epigenetic modifications ( While serving a physiologic function, senescence may also be associated with pathological conditions such as neurodegeneration and atherosclerosis, cancer and immune system dysregulation