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By binding with NCOA4, it destroyed the protein-protein interaction between NCOA4 and FTH1, blocked iron autophagy dependent on NCO A4, and reduced Fe 2+ in intracellular LIP, thus inhibiting ferroptosis

It has been studied internationally in areas including infection, immune dysfunction, cancer support, and critical illness

Deletion of the Candida albicans histidine kinase gene CHK1 improves recognition by phagocytes through an increased exposure of cell wall -1,3-glucans

Bind or No Bind Pull down assays offer a binary "yes" or "no" answer regarding any possible interaction between two proteins, thus establishing this technique as essential for the study of cellular pathways via protein-protein interactions