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Structural analysis was conducted using UCSF ChimeraX (v1.7) ( 42 ) and PDBePISA ( 57 )

Science and Technology Development Plan Project of Jilin Province, China (20240601022RC) Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

Peroxiredoxin 5 (Prx5) decreases LPS-induced microglial activation through regulation of Ca(2+)/calcineurin-Drp1-dependent mitochondrial fission