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ApoC-II was added at a concentration of 1 M to increase LPL activity

Furthermore, mitochondrial dysfunction promotes NLRP3 inflammasome assembly and caspase-1 activation, leading to the secretion of pro-inflammatory cytokines like IL-1, which are associated with the aberrant activation of CDK5 [53, 54]

Pregnant or breastfeeding individuals (unless approved by a provider)

For example, while almost all assays rely on ApoC-II mediated activation of LPL, the source of ApoC-II can range from serum samples taken from individuals or a pool of healthy individuals ( However, it is important to note that even following our recommendations, the 3 H-triolein-based assay still requires specialized equipment and accommodations for using radioactive isotopes and remains low-throughput compared to the 96-well plate format colorimetric and fluorometric methods of detecting LPL activity