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Supplementation with tocotrienols from Bixa orellana improves the in vivo efficacy of daptomycin against methicillin-resistant Staphylococcus aureus in a mouse model of infected wound

Moreover, understanding the temporal dynamics of metabolic changes enables the design of intervention strategies tailored to specific metabolic states or cell cycle stages, which holds promise for reducing the risk of adaptive resistance and increasing the precision and durability of treatments