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In my practice (and with my family), Ive taken to addressing not just Lp(a) directly, but also the underlying Lp(a) pathogenic mechanisms and other CVD risk factors with the goal of reducing the impact of high circulating Lp(a) on multiple fronts

(6) Although historically used as an organophosphate antiglaucoma agent, echothiophate is now largely obsolete because safer and more effective therapies, including prostaglandin analogs and topical adrenergic antagonists, have replaced its routine clinical use

Interestingly, the chronological life span (CLS) was lowered in the gsh1 strain cultured with 10% glucose but not under dietary restriction