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Taverne, Y

Clin Immunol 159:122127

Thus, benfotiamine was shown to be effective in suppressing both inflammation and oxidative stress, two hallmarks of chronically activated microglia [19]

ROC analysis based on pathway scores revealed that pathways such as alanine, aspartate, and glutamate metabolism, inositol phosphate metabolism, and mitochondrial beta-oxidation of unsaturated fatty acids exhibited an AUC greater than 0.8 in the PBMC data (Table S16)