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Its concentration decreases significantly with age, from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60

The auto-brewery syndrome is an understudied area, and it is unclear whether the disease is rare or whether it is rarely diagnosed

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Methods Patients who underwent PEID for lumbar disc herniation (LDH) were enrolled and randomly assigned to the single surgery (SS) group, where disc removal was performed via PEID alone, or the combined treatment (CT) group, which received epidural injections of dexamethasone and VB12 alongside surgery