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19 Moreover, the copper-dependent transcription factor ATOX1 contributes to tumor angiogenesis and vascular remodeling by modulating the platelet-derived growth factor signaling pathway and activating the ATP7A-mediated LOX signaling pathway

Nonetheless, have in mind that these studies were subjected to a long-term period of B deficiency, therefore, it cannot be ruled out that the changes in gene regulation are an indirect effect due to poor cellular development of the plants