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Production of authentic SARS-CoV M(pro) with enhanced activity: Application as a novel tag-cleavage endopeptidase for protein overproduction

However, it highlights the possibility of the AMPK-regulated modulation of mTORC2 increasing therapeutic sensitivity, possibly providing dual therapies that control these signaling pathways

When phorbol 12-myristate 13-acetate (PMA)treated human liver cancer cell lines (HepG2 and Hep3B) were incubated with 6G, the activity of matrix metalloproteinase-9 (MMP-9) was reduced, while an increase in the expression of tissue inhibitor metalloproteinase-1 (TIMP-1) protein was observed in both cell lines

Dickerhoff, J., Brundridge, N., McLuckey, S