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(Basel) 13, 1725

Imaging 51, 283296

Testosterone is crucial for male reproductive tissue development, sperm production, and overall sexual health ( 2.5 Molecular mechanisms linking glucose metabolism and male reproductive dysfunction in diabetes Male fertility is affected by Diabetes-induced dysregulation of glucose metabolism through several interconnected molecular pathways: 2.5.1 Pancreatic -amylase and intestinal -glucosidase These enzymes break down complex carbs into glucose, inhibiting their function and lowering hyperglycemia after meals

While these findings provide preliminary mechanistic insights, further clinical investigations are required to validate the therapeutic potential of targeting DHODH in combination with CIRT