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Why this trial matters: First triple hormone receptor agonist showing major Phase III weight-loss efficacy Delivers weight-loss outcomes far beyond many current therapies Suggests a potential new metabolic and obesity care benchmark Semaglutide Shows Consistent Liver Benefits in MASH In the Phase III ESSENCE study, once-weekly semaglutide 2.4 mg significantly increased rates of steatohepatitis resolution and fibrosis improvement on liver biopsy in adults with metabolic dysfunction-associated steatohepatitis (MASH), compared with placebo

[Abstract]2022 Sep 24:622:129-135

Among the 23 compounding pharmacies supplying those businesses, four did not have licenses required for sterile compounding, while several others had recent disciplinary actions or FDA warning letters tied to sterile compounding practices, according to the study

This may include more frequent blood glucose monitoring and ensuring adequate fluid intake