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Baldwin JM

However, the regulatory framework for drug development relies heavily on animal toxicology precisely because it does provide meaningful safety signals

Plates were incubated at 37 C for 1 hour, and absorbance was measured at 450 nm using a microplate reader (SpectraMax iD3, Molecular Devices, San Jose, CA, USA)

For dogs - who have shorter digestive tracts than humans - this improved delivery mechanism is especially important for getting a meaningful therapeutic dose