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Foci of extramedullary hematopoiesismature and/or immature erythroid and myeloid cell aggregates without accompanying hepatocyte necrosis

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The development of calcium-free, aluminum-free oral phosphate binders such as sevelamer-HCl (329-331), sevelamer carbonate (332,333), lanthanum carbonate (334-336), sucroferric oxyhydroxide (337), and ferric citrate (338) allows controlling hyperphosphatemia without the potential danger of calcium overload

Surgical scars, tattoos and piercings can also be affected as well as jewelry rubbing on your skin or your shoe/sock rubbing on your feet