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---------- For use in managing Vitamin B12 deficiencies associated with cobalt deficiency, inadequate intake, or intestinal malabsorption in cattle, sheep, swine, and horses

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DHEAS, which is structurally similar to PregS except for substitution of carbonyl oxygen for the acetyl group at C17 on the steroid D ring, potentiates NMDA-mediated Ca 2+ currents and inhibits GABA A R-mediated chloride currents (124, 128131)