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The anemia of individual 1 spontaneously resolved when he was 13 years old, indicating a clonal genetic reversion event

The maxima were enumerated as this provided a more accurate presentation of individual cells clumped together, in comparison to simple thresholding

Relative rates of protein synthesis were measured via [ 35 S]-methionine incorporation into newly synthesized proteins in Tsc2 +/+ and Tsc2 -/- cells treated with control siRNAs or Tsc2 -/- cells treated with siRNAs targeting ATF4 or Rheb, the small GTPase target of TSC2 that is an essential upstream activator of mTORC1

J Biol Agric Health 2(6):33 Kanoni S, Nettleton JA, Hivert M-F, Ye Z, van Rooij FJA, Shungin D, Sonestedt E, Ngwal JS, Wojczynski MK, Lemaitre RN, Gustafsson S, Anderson JS et al (2011) Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant a 14-cohort meta-analysis