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In reality, the human body tightly regulates blood pH between 7.35 and 7.45, and dietary bicarbonate has negligible influence on this system

Arrived sooner than I expected

Given that this approach uses a selective ion pair technique, not a full scan technique like others, it can improve sensitivity by up to two orders of magnitude and the linear response over a wide dynamic range up to five orders of magnitude compared to full scan technique (Lange et al., 2008)

This aligns with the position of major medical organizations, including the American Cancer Society and National Cancer Institute, which do not recognize coffee enemas as having any proven therapeutic value