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According to the Centers for Disease Control and Prevention, many Americans have at least one micronutrient deficiency due to factors such as poor diet, age-related hormonal changes, and impaired nutrient absorption related to digestive disorders---yet many remain undiagnosed

Cao, X.-G., Li, X.-X., Bao, Y.-Z., Xing, N.-Z

However, current evidence demonstrates limited clinical utility for available immunotherapeutics in GBM, due to a highly immunosuppressive TME and metabolic characteristics that impair anti-tumor immune response

Moreover, human DCs primed with lactic acid bacteria can promote both the proliferation and cytotoxic activity of NK cells, resulting in an elevated output of IFN- (194)