Vimentin intermediate filaments are degraded in the deeper lens cortex, well after the loss of membrane-bound organelles
The release of cathepsin D induced necroptosis through the proteolysis of caspase-8 and promotion of RIPK1 activation, implying that lysosomal dysfunction might be crucially involved in the onset of necroptosis 9
10.1523/JNEUROSCI.2329-14.2014 130 LiL.YangX

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