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High blood pressure (hypertension) is usually regulated by angiotensin-converting enzyme (ACE) via the kinin-kallikrein system (KKS) and the renin-angiotensin-aldosterone system (RAAS)

The authors synthesized evidence that HGF/c-Met signaling is essential for brain development, synaptic plasticity, and cognitive function, with disruption of this pathway associated with cognitive decline in aging and neurodegenerative diseases