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Phosphatidylcholine, which can be a source of choline, is fat-soluble

Am J Health Syst Pharm (2010) 67:44958

Ashwagandha also influences monoaminergic systems, but its effects are largely indirect, arising from normalization of hypothalamic-pituitary-adrenal (HPA) axis hyperactivity, modulation of GABAergic tone, and attenuation of stress-induced neurotransmitter imbalance