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In people with normal absorption, deficiencies have been reported only in strict vegetarianswho consume no products of animal origin (including no milk products or eggs)

elegans , and mammalian cells resulted in increased mitochondrial function and biogenesis, UPR mt , and antioxidant response gene expression 108110

This offers a degree of precision that can be very advantageous in a research setting

B12 deficiency isn't just a problem for vegans The Framingham Offspring study found that 39% of the general population may be in the low normal and deficient B12 blood level range, and it was not just vegetarians or older people