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Current investigations are focused on understanding whether NNMT inhibition might influence cancer progression or aggressiveness

Short-term Western diet intake promotes IL-23mediated skin and joint inflammation accompanied by changes to the gut microbiota in mice

Randomized trials have shown that folate and other nutritional supplementations have a significant effect in treating the treatment-resistant depression [19,20]

The strongest published finding is from the foundational Biochemical Pharmacology study by Neelakantan et al.: in diet-induced obese mice, daily 5-Amino-1MQ administration produced reductions in body weight, white adipose tissue mass, and adipocyte size without any significant change in food intake