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Description

Highly sensitive Curcumin-conjugated nanotheranostic platform for detecting amyloid-beta plaques by magnetic resonance imaging and reversing cognitive deficits of Alzheimer's disease via NLRP3-inhibition

In renal fibrosis, endoplasmic reticulum stress (ERS) activates iron-related apoptotic EMT through the XBP1-HRD1-NRF2 signaling pathway, offering new insights into mechanisms and potential treatments for EMT progression [105]

However, the latest research shows that sorafenib does not trigger ferroptosis through inhibition of System X c [25]

For analysis of genes expressed, TaqMan probes for human IFNG , IFITM3 , IFI27 , IFI44L , IFIT1 , MX1 , ISG15 , MX2 , RSAD2 and SIGLEC1 , mouse Ndusf8 , Sdha , Sdhb , Sdhc , Txnrd1 , Got1 , Arg1 , Tgfb1 , Ccl2 , Ccl3 , Fn1 , Mmp2 and Mmp12 or viral N1 and N2 (SARS-CoV-2) (IDT) were used