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Due to the risk of respiratory depression with concomitant use of muscle relaxants and opioids, consider recommending or prescribing an opioid overdose reversal agent (see WARNINGS)

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Pharmacological GLS inhibition causes a shortage in multiple TCA cycle intermediates, among which -ketoglutarate, succinate and fumarate

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doi: 10.6133/apjcn.2007.16.2.01 104

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