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If continued worsening occurs, combination therapy of LABA plus LAMA is recommended

A prominent example is hematide, a dimeric peptide, known also as a PEGylated peptide-based erythropoiesis stimulating agent [265]

The combined preventive and therapeutic administration strategy used in this study appears to have successfully avoided some of the negative consequences of DSIP administration during the occlusion period, which might have occurred with different timing or dosages