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Prospective studies are warranted to vali- date this threshold and dene precise therapeutic targets

Takahashi et al 245 used the technique layer-by-layer surface modification to modify phosphatidylcholine-gold nanorods (PC-NR) with polyethylenimine (PEI) and bovine serum albumin (BSA) which showed greater stability in electrolyte buffer solution and as a result prevented their aggregation under physiological conditions and caused increased uptake of the nanoparticles and cellular binding

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It provides exfoliation benefits without the aggressive penetration that can trigger irritation