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Achieving this objective will require more sophisticated genetic models, such as knock-in mice expressing NIK mutants that retain kinase activity but are uncoupled from IKK activation

Likewise, M2 macrophages released IL-8, which supported prostate carcinogenesis through the STAT3/metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) pathway [97]

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This potential interaction has been suggested as a contributing factor in tissue regeneration models