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A number of metabolic disorders, including dyslipidemia, glucose intolerance, insulin resistance, and obesity, play important roles in the induction of ED, which is particularly prevalent in many middle-aged and elderly patients [7]

Thus, in terms of the functional theory of compensatory renal hypertrophy, these findings strongly emphasize an improved function of the remaining kidney

Discussion Despite previous reports that high infiltration of M1-like macrophage was associated with better survival outcome, we found that transcriptomically defined M1 high tumors were not associated with favorable survival outcome with regards to OS, DSS, and DFS