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Kennaway DJ

Turchan-Cholewo J, Dimayuga VM, Gupta S, Gorospe RM, Keller JN, Bruce-Keller AJ

Reduction of the TXNIP interdomain disulphide bond between Cys63 and Cys190 would make Cys63 available to form an interprotomer disulphide linkage with Cys247 of another TXNIP molecule, as observed in in vivo co-immunoprecipitation and mass spectrometry experiments (Fig

El inconveniente sera el enmascaramiento del diagnstico neonatal, es decir, no apareceran los signos bioqumicos que permitan confirmar el diagnstico inmediatamente despus del nacimiento