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FEMALE INFERTILITY As with male fertility, oxidative stress or reactive oxygen species (ROS) in the female reproductive system, at low levels, is important in the mediation of processes such as hormone signaling, egg maturation, folliculogenesis (follicle growth cycle), fallopian tube function, proper production of hormones from the ovaries, changes in the uterine lining throughout the cycle, various functions throughout pregnancy, and initiation of labour

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This disruption is caused by inflammatory cytokines (e.g., TNF-, IL-1, IL-6), oxidative stress, and matrix metalloproteinases (MMPs), which deteriorate tight junction components and deteriorate barrier permeability [137, 149]

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