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observed that this effect increased with a higher SEV exposure time, though there was no difference when the total exposure was divided into multiple smaller time intervals (single 6 h exposure vs

Concomitant with these results, immunofluorescence for -smooth muscle actin (SMA) indicated reduced presence of hepatic stellate cells, the main cells driving fibrogenesis 3,51 , in livers from mice treated with AAV8-AGXT (Fig

From this, mitochondrial dysfunction can take place which not only leads to the formation of free radicals and lower ATP (energy) production, but is heavily linked to insulin resistance