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Moreover, ox-LDL triggers the immune response, damaged endothelial cells are activated and express monocyte chemoattractant proteins (MCP)-1 and 8, intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), E-selectin, P-selectin and other inflammatory factors (68)

Browning intensity Figure 3A and B shows the absorbance at 420 nm (A420nm) and the CIEL*a*b* blueyellow component (b*) of the various samples as indicators of browning intensity

10.3969/j.issn.1001-5256.2017.12.002 177 ZhangZ.ChangQ.ZhuM.HuangY.HoW

In an ApoE / mouse model of AS, PA/ASePSD generated strong photoacoustic signals at plaque sites, whereas signals were negligible in normal mice