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Targeting HO-1 may provide new strategies for the prevention and treatment of diabetes

The difference of kinetics between Day 1 and Day 22 for single dose and repeated dose, respectively, was more easily shown in Fig

The standard 4-5 mL of bac water for a 50 mg GHK-Cu vial brings concentration into the 10-12.5 mg/mL range, well within solubility limits and producing comfortable injection volumes for 2-3 mg doses

Cell lines All mammalian cells were obtained from Columbia University Cancer Cell Bank and cultured following ATCC recommended protocols and in medium supplemented with 10% fetal bovine serum (FBS, Thermo Fisher Scientific 26400044) and 1% Penicillin-Streptomycin (Thermo Fisher Scientific 15140122)