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The mRNA expression of kisspeptin-1 (KiSS-1) and its receptor, GPR54, which are critical for GnRH neuron function, remains stable after prolonged F treatment in animal models [173] (Fig

But, light and oxygen can change its effectiveness

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References : J Jang, HG Hur, MJ Sadowsky, MN Byappanahalli, T-Yan, S Ishii - Environmental Escherichia coli: ecology and public health implications-a review - J Appl Microbiol