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Metabolic pathway analysis was performed via MetaboAnalyst 6.0, which identified 10 significantly enriched pathways, including glutathione metabolism, porphyrin metabolism, thiamine metabolism, central carbon metabolism, and several amino acid biosynthesis pathways (Figure 2C)

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Groups of 6-7 Chinese hamsters (male and female) received 0.01, 0.1, or 0.5 mg acetaldehyde/kg body weight in saline by single intraperitoneal injection and were killed 24 h later