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10.1016/j.mce.2021.111464 90 RenQ.SunQ.FuJ

40 This mechanistic understanding highlights potential therapeutic avenues targeting ferroptosis for mitigating APAP-induced liver injury

Steps include: - Prepare coffee in plunger - Allow to cool - Set your space - Pour coffee into enema bag - Insert the hose tip - Unclamp and allow coffee to flow in - Ideally hold for 12-15 minutes - Sit on toilet to release Once finished, rinse enema bag with water, add cleaner and hang to dry