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Carere J, et al

The reduced gene expression or deletion of MET in vivo in mice results in altered synapse maturation (reviewed in Autism spectrum disorder is associated with deficits in the ontogeny of neural circuits ( MET promoter region in more than 200 families with ASD (Figure 3)

Ongoing pressure keeps stress hormones elevated, which over time can affect sleep, digestion, blood pressure, and the immune system, so calming the mind alone is rarely enough